formaldehyde

Synonyms: "formalin", "methanal", "formol", "paraformaldehyde", "Methylene oxide", "Oxomethane", "Paraform", "Formic aldehyde", "Oxymethylene", "Methyl aldehyde", "Formalith", "Fannoform", "Formaldehyde solution", "Superlysoform", "Methaldehyde", "Morbicid", "Formalina", "Lysoform", "Karsan", "Formaline", "Oxomethylene", "Formaldehyd", "Polyoxymethylene", "Aldehyde formique", "FYDE", "Formaldehyde, gas", "Formalin 40", "Aldeide formica", "30525-89-4", "Oplossingen", "Dormol", "Polyformaldehyde", "Formalin-loesungen", "Paraformic aldehyde", "Rcra waste number U122", "Aldacide", "Paraformaldehydum", "Aldehyd".

Source: Formaldehyde is commonly used as an antimicrobial, preservative, nail hardener as as an industrial reagent for the production of numerous materials such as plastics and resins.

Identifiers:

IUPAC Name: formaldehyde
CAS Number: 50-00-0
PubChem ID: 712
InChiKey: WSFSSNUMVMOOMR-UHFFFAOYSA-N
Canonical SMILES: C=O

Structural Properties:

Molecular Formula: CH₂O
Molecular Weight: 30.026

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 1
Number of atoms different from hydrogen: 2

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Patel KG, Bhatt HV, Choudhury AR. 2003. Alteration in thyroid after formaldehyde (HCHO) treatment in rats. Ind Health 41(3):295-297. DOI: 10.2486/indhealth.41.295. URL: https://www.jstage.jst.go.jp/article/indhealth1963/41/3/41_3_295/_article.
Rager JE, Smeester L, Jaspers I, Sexton KG, Fry RC. 2011. Epigenetic changes induced by air toxics: formaldehyde exposure alters miRNA expression profiles in human lung cells. Environ Health Perspect 119(4):494-500. DOI: 10.1289/ehp.1002614. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080931/.
Soffritti M, Belpoggi F, Lambertin L, Lauriola M, Padovani M, Maltoni C. 2002. Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in rats. Ann N Y Acad Sci 982:87-105. DOI: 10.1111/j.1749-6632.2002.tb04926.x. URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2002.tb04926.x/full.
Thrasher JD, Kilburn KH. 2001. Embryo toxicity and teratogenicity of formaldehyde. Arch Environ Health 56(4):300-311. DOI: 10.1080/00039890109604460. URL: http://www.tandfonline.com/doi/abs/10.1080/00039890109604460?journalCode=vzeh20.