2-ethoxyethanol
Synonyms: "cellosolve","oxitol", "ethyl cellosolve", "ethylene glycol monoethyl ether", "ethyl glycol", "ethylene glycol ethyl ether", "Dowanol EE", "Cellosolve solvent", "2-Ethoxyethyl alcohol", "Plastiazan 60", "Poly-Solv EE", "Solvid", "Ethylethylene glycol", "Jeffersol EE", "Glycol monoethyl ether", "2-Ethoxyethan-1-Ol", "Bikanol E 1", "Solvulose", "EGEE", "Ektasolve EE", "Dowanol 8", "Celosolv", "Ethyl ethylene glycol", "Glycol ether EE".
Source: 2-ethoxyethanol is used as solvent in organic synthesis and also in paints, coatings, inks, cleaners, polishes, brake fluids and jet fuels.
Identifiers:
IUPAC Name: 2-ethoxyethanol
CAS Number: 110-80-5
PubChem ID: 8076
InChiKey: ZNQVEEAIQZEUHB-UHFFFAOYSA-N
Canonical SMILES: CCOCCO
Structural Properties:
Molecular Formula: C4H10O2
Molecular Weight: 90.122
Pharmacophore Features:
Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 6
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
Tonkin EG, Cooper M, Lollini LO, Day-Lollini PA, Allard J, Kolaja KL, Platz SJ, Chanda SM. 2009. Testicular gene expression profiling following 2-methoxyethanol and 2-ethoxyethanol exposure in male rats reveals abnormal expression of the actin binding protein cortactin in degenerating spermatocytes. Toxicol Lett 190(2):193-201. DOI: 10.1016/j.toxlet.2009.07.017. URL: https://www.sciencedirect.com/science/article/pii/S0378427409013447.