amitraz
Synonyms: "taktic", "triazid", "mitac", "azaform", "BAAM", "mitaban", "acarac", "azadieno", "ectodex"
Source: amitraz is a formamidine pesticide widely used in agriculture and veterinary medicine as an insecticide and acaricide.
Identifiers:
IUPAC Name: N'-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)iminomethyl]-N-methylmethanimidamide
CAS Number: 33089-61-1
PubChem ID: 36324
InChiKey: QXAITBQSYVNQDR-UHFFFAOYSA-N
Canonical SMILES: CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C
Structural Properties:
Molecular Formula: C19H23N3
Molecular Weight: 293.406
Pharmacophore Features:
Number of bond donors: 0
Number of bond acceptors: 3
Number of atoms different from hydrogen: 22
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
Costa LG, Olibet G, Murphy SD. 1988. Alpha2-adrenoceptors as a target for formamidine pesticides: In vitro and in vivo studies in mice. Toxicol Appl Pharmacol 93(2):319-328.
Palermo-Neto J, Florio JC, Sakate M. 1994. Developmental and behavioral effects of prenatal amitraz exposure in rats. Neurotoxicol Teratol 16(1):65-70.