carbofuran
Synonyms: "furadan", "curaterr", "yaltox", "furadan 3G", "carbofurane", "pillarfuran", "chinufur", "crisfuran"
Source: carbofuran is a broad spectrum carbamate pesticide that kills insects, mites and nematodes on contact or after ingestion. It is used against soil and foliar pests of field, fruit, vegetable and forest crops.
Identifiers:
IUPAC Name: (2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate
CAS Number: 1563-66-2
PubChem ID: 2566
InChiKey: DUEPRVBVGDRKAG-UHFFFAOYSA-N
Canonical SMILES: CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C
Structural Properties:
Molecular Formula: C12H15NO3
Molecular Weight: 221.252
Pharmacophore Features:
Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 16
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
Casale GP, Vennerstrom JL, Bavari S, Wang T. 1993. Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. Immunopharmacology & Immunotoxicology 15(2 & 3):199-215.
Yousef MI, Bertheussen K, Ibrahim HZ, Helmi S, Seehy MA, Salem MH. 1996. A sensitive sperm-motility test for the assessment of cytotoxic effect of pesticides. Journal of Environmental Science & Health Part B 31(1):99-115.