pronamide

Synonyms: "propyzamide", "KERB", "pronamid", "clanex", "3,5-dichloro-N-(1,1-dimethylpropynyl)benzamide"

Source: pronamide is a selective, systemic, pre- and post-emergence herbicide that acts by inhibiting plant cell division.

Identifiers:

IUPAC Name: 3,5-dichloro-N-(2-methylbut-3-yn-2-yl)benzamide
CAS Number: 23950-58-5
PubChem ID: 32154
InChiKey: PHNUZKMIPFFYSO-UHFFFAOYSA-N
Canonical SMILES: C(C)(C#C)NC(=O)C1=CC(=CC(=C1)Cl)Cl

Structural Properties:

Molecular Formula: C12H11Cl2NO
Molecular Weight: 256.128

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 1
Number of atoms different from hydrogen: 16

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
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Hurley PM, Hill RN, Whiting RJ. 1998. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents [review]. Environ Health Perspect 106(8):437-445.

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