perfluorodecanoic acid

Synonyms: "perfluorodecanoic acid", "nonadecafluorodecanoic acid", "PFDA", "perfluoro-N-decanoic acid", "nonadecafluoro-n-decanoic acid", "2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluorodecanoic acid", "perfluorocapric acid", "nonadecafluorocapric acid".

Source: perfluorodecanoic acid is a member of a class of perfluorinated alkanoic acids commonly used as lubricants, plasticizers, wetting agents and corrosion, as well as emulsifiers and surfactants in fluoropolymer manufacturing.

Identifiers:

IUPAC Name: 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluorodecanoic acid
CAS Number: 335-76-2
PubChem ID: 9555
InChiKey: PCIUEQPBYFRTEM-UHFFFAOYSA-N
Canonical SMILES: C(=O)(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O

Structural Properties:

Molecular Formula: C10HF19O2
Molecular Weight: 514.086

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 21
Number of atoms different from hydrogen: 31

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2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

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Van Rafelghem, M.J., Inhorn, S.L. and Peterson, R.E., 1987. Effects of perfluorodecanoic acid on thyroid status in rats. Toxicology and applied pharmacology, 87(3), pp.430-439. DOI: 10.1016/0041-008X(87)90248-1. URL: https://www.ncbi.nlm.nih.gov/pubmed/3564018.
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Wolf CJ, Takacs ML, Schmid JE, Lau C, Abbott BD. 2008. Activation of mouse and human peroxisome proliferator-activated receptor alpha by perfluoroalkyl acids of different functional groups and chain lengths. Toxicol Sci 106(1):162-171. DOI: 10.1093/toxsci/kfn166. URL: https://academic.oup.com/toxsci/article/106/1/162/1709456.