methanol

Synonyms: "methanol", "methyl alcohol", "wood alcohol", "carbinol", "methylol", "methyl hydroxide", "monohydroxymethane".

Source: Methanol occurs naturally in the environment. It is used as an antifreeze, solvent and fuel, among others.

Identifiers:

IUPAC Name: methanol
CAS Number: 67-56-1
PubChem ID: 887
InChiKey: OKKJLVBELUTLKV-UHFFFAOYSA-N
Canonical SMILES: CO

Structural Properties:

Molecular Formula: CH4O
Molecular Weight: 32.042

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 1
Number of atoms different from hydrogen: 2

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
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Burbacher TM, Grant KS, Shen DD, Sheppard L, Damian D, Ellis S, Liberato N. 2004. Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): reproductive performance and birth outcome. Neurotoxicol Teratol 26(5):639-650. DOI: 10.1016/j.ntt.2004.06.001. URL: http://www.sciencedirect.com/science/article/pii/S0892036204000819Cummings AM. 1993. Evaluation of the effects of methanol during early pregnancy in the rat. Toxicology 79(3):205-214. DOI: 10.1016/0300-483X(93)90212-B. URL: https://www.sciencedirect.com/science/article/pii/0300483X9390212B.
Gonzalez-Quevedo A, Obregon F, Urbina M, Rousso T, Lima L. 2002. Effect of chronic methanol administration on amino acids and monoamines in retina, optic nerve, and brain of the rat. Toxicol Appl Pharmacol 185(2):77-84. DOI: 10.1006/taap.2002.9477. URL: http://www.sciencedirect.com/science/article/pii/S0041008X02994779?via%3Dihub.

Youssef AF, Baggs RB, Weiss B, Miller RK. 1997. Teratogenicity of methanol following a single oral dose in Long-Evans rats. Reprod Toxicol 11(4):503-510. DOI: 10.1016/S0890-6238(97)00017-8. URL: https://www.sciencedirect.com/science/article/pii/S0890623897000178.

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