1-methyl-2-pyrrolidinone

Synonyms: "N-methylpyrrolidone", "1-methylpyrrolidin-2-one", "1-methyl-2-pyrrolidone", "methylpyrrolidone", "M-pyrol", "N-methyl-2-pyrrolidinone", "N-methylpyrrolidinone", "1-methylpyrrolidinone", "1-methylpyrrolidone", "1-methylazacyclopentan-2-one", "1-methyl-5-pyrrolidinone", "NMP", "N-methyl-gamma-butyrolactam", "N-methylpyrrolidin-2-one", "n-methyl-pyrrolidone", "Methyl-2-pyrrolidinone", "1-methyl-2-pyrrolidon", "methylpyrrolidinone", "Methyl pyrrolidone", "N-methyl pyrrolidone", "1,1-bis(4-hydroxyphenyl)cyclohexane".

Source: 1-methyl-2-pyrrolidinone is widely used as a solvent for coal-derived products and as eluent in size exclusion chromatography.

Identifiers:

IUPAC Name: 1-methylpyrrolidin-2-one
CAS Number: 872-50-4
PubChem ID: 13387
InChiKey: SECXISVLQFMRJM-UHFFFAOYSA-N
Canonical SMILES: CN1CCCC1=O

Structural Properties:

Molecular Formula: C₅H₉NO
Molecular Weight: 99.133

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 1
Number of atoms different from hydrogen: 7

Downloads

2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

Search Similar molecules

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Sitarek, K. and Stetkiewicz, J., 2008. Assessment of reproductive toxicity and gonadotoxic potential of N-methyl-2-pyrrolidone in male rats. International journal of occupational medicine and environmental health, 21(1), pp.73-80. DOI: https://doi.org/10.2478/v10001-008-0006-z. URL: https://www.degruyter.com/view/j/ijmh.2008.21.issue-1/v10001-008-0006-z/v10001-008-0006-z.xml.
Sitarek, K., Stetkiewicz, J. and W?sowicz, W., 2012. Evaluation of Reproductive Disorders in Female Rats Exposed to N?Methyl?2?Pyrrolidone. Birth Defects Research Part B: Developmental and Reproductive Toxicology, 95(3), pp.195-201. DOI: https://doi.org/10.1002/bdrb.21001 . URL: https://onlinelibrary.wiley.com/doi/full/10.1002/bdrb.21001.