propoxur
Synonyms: "baygon", "aprocarb", "sendran", "propoxure", "blattanex", "blattosep", "mrowkozol", "propotox", "propoxylor"
Source: propoxur is an insecticide used to control cockroaches, flies, mosquitoes, and lawn insects.
Identifiers:
IUPAC Name: (2-propan-2-yloxyphenyl) N-methylcarbamate
CAS Number: 114-26-1
PubChem ID: 4944
InChiKey: ISRUGXGCCGIOQO-UHFFFAOYSA-N
Canonical SMILES: CC(C)OC1=CC=CC=C1OC(=O)NC
Structural Properties:
Molecular Formula: C11H15NO3
Molecular Weight: 209.242
Pharmacophore Features:
Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 15
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
Klotz DM, Arnold SF, McLachlan JA. 1997. Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides. Life Sci 60(17):1467-1475.
Schmuck G, Mihail F. 2004. Effects of the carbamates fenoxycarb, propamocarb and propoxur on energy supply, glucose utilization and SH-groups in neurons. Arch Toxicol 78(6):330-337.