endosulfan

Synonyms: "benzoepin", "thiodan", "thionex", "thiosulfan", "chlorthiepin", "devisulphan", "endosulphan", "insectophene", "rasayansulfan"

Source: endosulfan is an organochlorine insecticide that can be used on a wide variety of vegetables and fruits, cotton, and ornamental plants.

Identifiers:

IUPAC Name: 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine-3-oxide
CAS Number: 115-29-7
PubChem ID: 3224
InChiKey: RDYMFSUJUZBWLH-UHFFFAOYSA-N
Canonical SMILES: C1C2C(COS(=O)O1)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl

Structural Properties:

Molecular Formula: C9H6Cl6O3S
Molecular Weight: 406,925

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 2
Number of atoms different from hydrogen: 19

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Toxicological Information

ACToR (Aggregated Computational Toxicology Resource)

HSDB (Hazardous Substances Data Bank)

CCRIS (Chemical Carcinogenesis Research Information System)

GENE-TOX

CTD (Comparative Toxicogenomics Database)

IRIS (Integrated Risk Information System)

ITER (International Toxicity Estimates for Risk)

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors


Banerjee BD, Hussain QZ. 1986. Effect of sub-chronic endosulfan exposure on humoral and cell-mediated immune responses in albino rats. Arch Toxicol 59(4):279-284.
Orton F, Rosivatz E, Scholze M, Kortenkamp A. 2011. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect 119(6):794-800.
Soto AM, Sonnenschein C, Chung KL, Fernandez MF, Olea N, Serrano FO. 1995. The E-SCREEN assay as a tool to identify estrogens: An update on estrogenic environmental pollutants. Environ Health Perspect 103 (Suppl. 7):113-122.

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Keywords


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