Synonyms: "chlorphenamidine", "chlorfenamidine", "galecron", "fundal", "chlorophenamidine", "ovatoxin", "ovatoxion", "acaron", "bermat"

Source: chlordimeform is an acaricide active mainly against motile forms of mites and ticks and against eggs and early instars of some Lepidoptera insects.


IUPAC Name: N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide
CAS Number: 6164-98-3
PubChem ID: 22544
Canonical SMILES: CC1=C(C=CC(=C1)Cl)N=CN(C)C

Structural Properties:

Molecular Formula: C10H13ClN2
Molecular Weight: 196.677

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 2
Number of atoms different from hydrogen: 13


2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Cooper RL, Barrett MA, Goldman JM, Rehnberg GL, McElroy WK, Stoker TE. 1994. Pregnancy alterations following xenobiotic induced delays in ovulation in the female rat. Fundam Appl Toxicol 22(3):474-480.

Costa LG, Olibet G, Murphy SD. 1988. Alpha2-adrenoceptors as a target for formamidine pesticides: In vitro and in vivo studies in mice. Toxicol Appl Pharmacol 93(2):319-328.

Goldman JM, Cooper RL, Laws SC, Rehnberg GL, Edwards TL, McElroy WK, Hein J. 1990. Chlordimeform-induced alterations in endocrine regulation within the male rat reproductive system. Toxicol Appl Pharmacol 104(1):25-35.

Stoker TE, Goldman JM, Cooper RL, McElroy WK. 1991. Influence of chlordimeform on alpha-adrenergic receptor-associated mechanisms of hormonal regulation in the rat: pituitary and adrenocortical secretion. Toxicology 69(3):257-268.

Wiltrout RW, Ercegovich CD, Ceglowski WS. 1978. Humoral immunity in mice following oral administration of selected pesticides. Bull Environ Contam Toxicol 20(3):423-431.

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