Synonyms: "carbaril", "sevin", "carylderm", "1-Naphthyl N-methylcarbamate", "caprolin", "carbatox", "carbavur", "carpolin"

Source: carbaryl is a general use carbamate pesticide that acts primarily as an insecticide, but is also competent as molluscicide and acaricide.


IUPAC Name: naphthalen-1-yl N-methylcarbamate
CAS Number: 63-25-2
PubChem ID: 6129
Canonical SMILES: CNC(=O)OC1=CC=CC2=CC=CC=C21

Structural Properties:

Molecular Formula: C12H11NO2
Molecular Weight: 201.221

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 1
Number of atoms different from hydrogen: 15


2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Casale GP, Vennerstrom JL, Bavari S, Wang T. 1993. Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. Immunopharmacology & Immunotoxicology 15(2 & 3):199-215.

Dieringer CS, Thomas JA. 1974. Effects of carbaryl on the metabolism of androgens in the prostate and liver of the mouse. Environ Res 7(3):381-386.

Hassan A. 1971. Pharmacological effects of carbaryl. I. The effect of carbaryl on the synthesis and degradation of catecholamines in the rat. Biochem Pharmacol 20(9):2299-308.

Klotz DM, Arnold SF, McLachlan JA. 1997. Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides. Life Sci 60(17):1467-1475.

Smalley HE, Curtis JM, Earl FL. 1968. Teratogenic action of carbaryl in beagle dogs. Toxicol Appl Pharmacol 13(3):392-403.

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