4'-hydroxypropiophenone

Synonyms: "paroxypropione", "4'-hydroxypropiophenone", "mepal", "paroxypropion", "proxiphenon", "frenantol", "frenohypon", "frenormon"

Source: 4'-hydroxypropiophenone is a pituitary gonadotrophic hormone inhibitor which has been used for the control of pituitary hyperactivity.

Identifiers:

IUPAC Name: 1-(4-hydroxyphenyl)propan-1-one
CAS Number: 70-70-2
PubChem ID: 6271
InChiKey: RARSHUDCJQSEFJ-UHFFFAOYSA-N
Canonical SMILES: CCC(=O)C1=CC=C(C=C1)O

Structural Properties:

Molecular Formula: C₉H₁₀O₂
Molecular Weight: 150.175

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 11

Downloads

2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

Search Similar molecules

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Schultz TW, Sinks GD, Cronin MTD. 2000. Effect of substituent size and dimensionality on potency of phenolic xenoestrogens evaluated with a recombinant yeast assay. Environ Toxicol Chem 19(11):2637-2642.