resorcinol

Synonyms: "1,3-benzenediol", "resorcin", "1,3-dihydroxybenzene", "m-hydroquinone", "m-hydroxyphenol", "m-dihydroxybenzene", "3-hydroxyphenol"

Source: resorcinol is one of the main natural phenols in argan oil. It is used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

Identifiers:

IUPAC Name: benzene-1,3-diol
CAS Number: 108-46-3
PubChem ID: 5054
InChiKey: GHMLBKRAJCXXBS-UHFFFAOYSA-N
Canonical SMILES: C1=CC(=CC(=C1)O)O

Structural Properties:

Molecular Formula: C6H6O2
Molecular Weight: 110,1106

Pharmacophore Features:

Number of bond donors: 2
Number of bond acceptors: 2
Number of atoms different from hydrogen: 8

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Toxicological Information

ACToR (Aggregated Computational Toxicology Resource)

HSDB (Hazardous Substances Data Bank)

CCRIS (Chemical Carcinogenesis Research Information System)

GENE-TOX

CTD (Comparative Toxicogenomics Database)

ITER (International Toxicity Estimates for Risk)

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors


Aiston S, Agius L. 1999. Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin. Diabetes 48(1):15-20.
Alanko J, Riutta A, Mucha I, Vapaatalo H, Metsa-Ketela T. 1993. Modulation of arachidonic acid metabolism by phenols: relation to positions of hydroxyl groups and peroxyl radical scavenging properties. Free Radic Biol Med 14(1):19-25.
Divi RL, Doerge DR. 1994. Mechanism-based inactivation of lactoperoxidase and thyroid peroxidase by resorcinol derivatives. Biochemistry (Mosc) 33(32):9668-9674.
Lindsay RH, Hill JB, Gaitan E, Cooksey RC, Jolley RL. 1992. Antithyroid effects of coal-derived pollutants. J Toxicol Environ Health 37(4):467-481.
Welsch F, Nemec MD, Lawrence WB. 2008. Two-generation reproductive toxicity study of resorcinol administered via drinking water to Crl:CD(SD) Rats. Int J Toxicol 27(1):43-57.

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