sulfamethazine

Synonyms: "sulfadimidine", "sulfadimezine", "sulfamezathine", "sulphamezathine", "sulfadimerazine", "sulfadimesin", "sulfadimesine", "sulfadimethyldiazine", "4,6-dimethylsulfadiazine", "4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide"

Source: sulfamethazine is an antimicrobial sulfur drug.

Identifiers:

IUPAC Name: 4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
CAS Number: 57-68-1
PubChem ID: 5327
InChiKey: ASWVTGNCAZCNNR-UHFFFAOYSA-N
Canonical SMILES: CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C

Structural Properties:

Molecular Formula: C12H14N4O2S
Molecular Weight: 278.330

Pharmacophore Features:

Number of bond donors: 2
Number of bond acceptors: 5
Number of atoms different from hydrogen: 19

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Evidence Supporting This Chemical as an Endocrine Disruptor
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Doerge DR, Divi RL. 1995 Jul. Porphyrin pi-cation and protein radicals in peroxidase catalysis and inhibition by anti-thyroid chemicals. Xenobiotica 25(7):761-767.

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