ethylene glycol monomethyl ether

Synonyms: "methyl cellosolve", "2-methoxyethanol", "ethylene glycol monomethyl ether", "methyl oxitol", "2-methoxy-1-ethanol", "monomethyl glycol"

Source: 2-methoxyethanol is used as a jet fuel de-icer. It is also used as a solvent for cellulose acetate, resins, dyes, and quick drying varnishes, enamels, nail polishes and wood stains.


IUPAC Name: 2-methoxyethanol
CAS Number: 109-86-4
PubChem ID: 8019

Structural Properties:

Molecular Formula: C3H8O2
Molecular Weight: 76,0944

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 5


2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

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Toxicological Information

ACToR (Aggregated Computational Toxicology Resource)

HSDB (Hazardous Substances Data Bank)

CCRIS (Chemical Carcinogenesis Research Information System)

CTD (Comparative Toxicogenomics Database)

IRIS (Integrated Risk Information System)

ITER (International Toxicity Estimates for Risk)

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Creasy DM, Flynn JC, Gray TJ, Butler WH. 1985. A quantitative study of stage specific spermatocyte damage following administration of ethylene glycol monomethyl ether in the rat. Experimental & Molecular Pathology 43(3):321-336.
Linder RE, Strader LF, Slott VL, Suarez JD. 1992. Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants. Reprod Toxicol 6(6):491-505.
Nagano K, Nakayama E, Oobayashi H, Nishizawa T, Okuda H, Yamazaki K. 1984. Experimental studies on toxicity of ethylene glycol alkyl ethers in Japan. Environ Health Perspect 57:75-84.

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