Synonyms: "taktic", "triazid", "mitac", "azaform", "BAAM", "mitaban", "acarac", "azadieno", "ectodex"

Source: amitraz is a formamidine pesticide widely used in agriculture and veterinary medicine as an insecticide and acaricide.


IUPAC Name: N'-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)iminomethyl]-N-methylmethanimidamide
CAS Number: 33089-61-1
PubChem ID: 36324
Canonical SMILES: CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C

Structural Properties:

Molecular Formula: C19H23N3
Molecular Weight: 293,406

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 3
Number of atoms different from hydrogen: 22


2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

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Toxicological Information

ACToR (Aggregated Computational Toxicology Resource)

HSDB (Hazardous Substances Data Bank)

CCRIS (Chemical Carcinogenesis Research Information System)

CTD (Comparative Toxicogenomics Database)

IRIS (Integrated Risk Information System)

ITER (International Toxicity Estimates for Risk)

Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Costa LG, Olibet G, Murphy SD. 1988. Alpha2-adrenoceptors as a target for formamidine pesticides: In vitro and in vivo studies in mice. Toxicol Appl Pharmacol 93(2):319-328.
Palermo-Neto J, Florio JC, Sakate M. 1994. Developmental and behavioral effects of prenatal amitraz exposure in rats. Neurotoxicol Teratol 16(1):65-70.

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