dichlorvos

Synonyms: "DDVP", "dichlorphos", "dichlorophos", "divipan", "equigard", "equigel", "atgard", "vapona"

Source: dichlorvos is an organophosphate insecticide widely used in developing countries.

Identifiers:

IUPAC Name: 2,2-dichloroethenyl dimethyl phosphate
CAS Number: 62-73-7
PubChem ID: 3039
InChiKey: OEBRKCOSUFCWJD-UHFFFAOYSA-N
Canonical SMILES: COP(=O)(OC)OC=C(Cl)Cl

Structural Properties:

Molecular Formula: C₄H₇Cl₂O₄P
Molecular Weight: 220.976

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 1
Number of atoms different from hydrogen: 11

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3D structure (.sdf)
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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Casale GP, Vennerstrom JL, Bavari S, Wang T. 1993. Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. Immunopharmacology & Immunotoxicology 15(2 & 3):199-215.

Timmons EH, Chaklos RJ, Bannister TM, Kaplan HM. 1975. Dichlorvos effects on estrous cycle onset in the rat. Lab Anim Sci 25(1):45-47.

Wyrobek AJ, Bruce WR. 1975. Chemical induction of sperm abnormalities in mice. Proceedings of the National Academy of Sciences USA 72(11):4425-4429.