Synonyms: "temik", "aldicarbe", "carbamyl", "sulfone aldoxycarb"

Source: aldicarb is a multi-use pesticide that controls populations of agriculturally-harmful insects and nematodes.


IUPAC Name: [(E)-(2-methyl-2-methylsulfanylpropylidene)amino] N-methylcarbamate
CAS Number: 116-06-3
PubChem ID: 9570071
Canonical SMILES: CC(C)(C=NOC(=O)NC)SC

Structural Properties:

Molecular Formula: C7H14N2O2S
Molecular Weight: 190.263

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 3
Number of atoms different from hydrogen: 12


2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Casale GP, Vennerstrom JL, Bavari S, Wang T. 1993. Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. Immunopharmacology & Immunotoxicology 15(2 & 3):199-215.

Hajoui O, Flipo D, Mansour S, Fournier M, Krzystyniak K. 1992. Immunotoxicity of subchronic versus chronic exposure to aldicarb in mice. Int J Immunopharmacol 14(7):1203-1211.

Kanayama T, Kobayashi N, Mamiya S, Nakanishi T, Nishikawa J. 2005. Organotin compounds promote adipocyte differentiation as agonists of the peroxisome proliferator-activated receptor [gamma]/retinoid X receptor pathway. Mol Pharmacol 67(3):766-774.

Klotz DM, Arnold SF, McLachlan JA. 1997. Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides. Life Sci 60(17):1467-1475.

Smulders CJ, Bueters TJ, Van Kleef RG, Vijverberg HP. 2003. Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase. Toxicol Appl Pharmacol 193(2):139-146.

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