trichlorfon

Synonyms: "metrifonate", "trichlorphon", "metriphonate", "chlorophos", "bilarcil", "dylox", "chlorofos", "dipterex", "foschlor"

Source: trichlorfon is a selective insecticide, meaning that it kills selected insects, but spares many or most other organisms.

Identifiers:

IUPAC Name: 2,2,2-trichloro-1-dimethoxyphosphorylethanol
CAS Number: 52-68-6
PubChem ID: 5853
InChiKey: NFACJZMKEDPNKN-UHFFFAOYSA-N
Canonical SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC

Structural Properties:

Molecular Formula: C₄H₈Cl₃O₄P
Molecular Weight: 257.437

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 12

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors

Nicolau GY. 1983. Circadian rhythms of RNA, DNA and protein in the rat thyroid, adrenal and testis in chronic pesticide exposure III. Effects of the insecticides (dichlorvos and trichlorphon). Rev. Roum. Morphology Embryology & Physiology 20(2):93-101.