trichloroethylene

Synonyms: "trichloroethene", "1,1,2-trichloroethene", "trilene", "trichlorethylene", "ethinyl trichloride", "ethylene trichloride", "1,1,2-trichloroethylene", "acetylene trichloride", "trethylene", "narcogen", "trielina", "chlorilen", "threthylen", "blancosolv", "trichloran", "trichloraethen", "threthylene", "crawhaspol", "trichloren", "germalgene", "densinfluat", "westrosol", "vestrol", "trielene", "circosolv", "cecolene", "algylen", "chlorylen", "trielin", "triasol", "lanadin", "blacosolv", "benzinol", "anamenth", "trieline", "petzinol", "narkosoid", "lethurin", "dukeron", "trilen".

Source: Trichloroethylene is used in paint strippers, rug cleaners, spot removers, typewritercorrection fluid and industrial cleaners.

Identifiers:

IUPAC Name: 1,1,2-trichloroethene
CAS Number: 79-01-6
PubChem ID: 6575
InChiKey: XSTXAVWGXDQKEL-UHFFFAOYSA-N
Canonical SMILES: C(=C(Cl)Cl)Cl

Structural Properties:

Molecular Formula: C2HCl3
Molecular Weight: 131.380

Pharmacophore Features:

Number of bond donors: 0
Number of bond acceptors: 0
Number of atoms different from hydrogen: 5

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
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Chia, S.E., Goh, V.H.H. and Ong, C.N., 1997. Endocrine profiles of male workers with exposure to trichloroethylene. American journal of industrial medicine, 32(3), pp.217-222. DOI: 10.1002/(SICI)1097-0274(199709)32:3<217::AID-AJIM6>3.0.CO,2-U . URL: https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1097-0274(199709)32:3%3C217::AID-AJIM6%3E3.0.CO,2-U.
Kumar, P., Prasad, A.K. and Dutta, K.K., 2000. Steroidogenic alterations in testes and sera of rats exposed to trichioroethylene (TCE) by inhalation. Human & experimental toxicology, 19(2), pp.117-121. DOI: 10.1191/096032700678815657. URL: http://journals.sagepub.com/doi/abs/10.1191/096032700678815657.

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