palmitic acid

Synonyms: "palmitic acid", "hexadecanoic acid", "cetylic acid", "n-hexadecanoic acid", "palmitate", "hexadecylic acid", "hydrofol", "n-hexadecoic acid", "1-pPentadecanecarboxylic acid", "pentadecanecarboxylic acid", "palmitinic acid", "hexaectylic acid", "Emersol 143", "Emersol 140", "Hystrene 8016", "Hystrene 9016", "1-hexyldecanoic acid", "hexadecoic acid", "palmitic acid", "palmitinsaeure", "Pristerene 4934", "Edenor C16", "Kortacid 1698", "Lunac P 95KC".

Source: Palmitic acid is a saturated fat. It's naturally found in some animal products like meat and dairy, as well as in palm and coconut oils.

Identifiers:

IUPAC Name: hexadecanoic acid
CAS Number: 57-10-3
PubChem ID: 985
InChiKey: IPCSVZSSVZVIGE-UHFFFAOYSA-N
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)O

Structural Properties:

Molecular Formula: C16H32O2
Molecular Weight: 256.430

Pharmacophore Features:

Number of bond donors: 1
Number of bond acceptors: 2
Number of atoms different from hydrogen: 18

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Evidence Supporting This Chemical as an Endocrine Disruptor
TEDX List of Potential Endocrine Disruptors
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Azevedo-Martins AK, Monteiro AP, Lima CL, Lenzen S, Curi R. 2006. Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. Toxicol In Vitro 20(7):1106-1113. DOI: 10.1016/j.tiv.2006.02.007. URL: http://www.sciencedirect.com/science/article/pii/S088723330600035X.
Beeharry N, Lowe JE, Hernandez AR, Chambers JA, Fucassi F, Cragg PJ, Green MH, Green IC. 2003. Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid. Mutat Res 530(1-2):27-33. DOI: 10.1016/S0027-5107(03)00134-9. URL: https://www.sciencedirect.com/science/article/pii/S0027510703001349.
Xiao J, Gregersen S, Pedersen SB, Hermansen K. 2002. Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells. Metabolism 51(2):155-162. DOI: 10.1053/meta.2002.29977. URL: http://www.metabolismjournal.com/article/S0026-0495(02)48208-X/pdf.

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